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Armed police were deployed and a man arrested after reports of an attack involving a large dog.
Gloucestershire Police said the incident happened at about 03:20 BST on Tuesday in the town of Newent in the Forest of Dean.
The force added there had been a "large and prolonged" police presence in the area since then.
The man who was attacked suffered puncture wounds to his arm and was taken to Gloucestershire Royal Hospital, where he remains.